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Peripheral virus-specific T-cell Interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis

BACKGROUND & AIMS: Interleukin-10 (IL-10) has been ascribed pro-viral but anti-fibrotic properties in chronic hepatitis C virus (HCV) infection. In this study, we examined the role of HCV-specific T-cell IL-10 response in patients with acute and chronic HCV infection. METHODS: Peripheral HCV-spe...

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Main Authors: Kaplan, David E., Ikeda, Fusao, Li, Yun, Nakamoto, Nobuhiro, Ganesan, Sutharsan, Valiga, Mary E., Nunes, Frederick A., Reddy, K. Rajender, Chang, Kyong-Mi
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430081/
https://ncbi.nlm.nih.gov/pubmed/18384906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2008.01.030
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