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Mutations Generated in Human Immunodeficiency Virus Type 1 Long Terminal Repeat During Vertical Transmission Correlate With Viral Gene Expression
We determined the effect of mutations generated in HIV-1 LTR on viral gene expression in six mother-infant pairs following vertical transmission. We show that the functional domains critical for LTR function, the promoter (TATAA), enhancers (three Sp-I and two NFκB sites), the modulatory region (two...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430019/ https://ncbi.nlm.nih.gov/pubmed/18313715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.01.048 |
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