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Spontaneous development of a pancreatic exocrine disease in CD28-deficient NOD mice

Autoimmune pancreatitis (AIP) is a heterogeneous autoimmune disease in humans characterized by a progressive lymphocytic and plasmacytic infiltrate in the exocrine pancreas. In this study, we report that Treg-deficient NOD.CD28KO mice spontaneously develop AIP that closely resembles the human diseas...

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Huvudupphovsmän: Meagher, Craig, Tang, Qizhi, Fife, Brian T., Bour-Jordan, Helene, Wu, Jenny, Pardoux, Cecile, Bi, Mingying, Melli, Kristin, Bluestone, Jeffrey A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429990/
https://ncbi.nlm.nih.gov/pubmed/18523243
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