Reduced paxillin expression contributes to the antimetastatic effect of 4-hydroxycoumarin on B16-F10 melanoma cells

BACKGROUND: 4-Hydroxycoumarin (4-HC) is a coumarin that lacks anticoagulant activity. 4-HC affects the cytoskeletal stability and decreases cell adhesion and motility of the melanoma cell line B16-F10. Together with integrins and other cytoskeletal proteins, paxillin participates in the regulation o...

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Hlavní autoři: Velasco-Velázquez, Marco A, Salinas-Jazmín, Nohemí, Mendoza-Patiño, Nicandro, Mandoki, Juan J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Primary Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429896/
https://ncbi.nlm.nih.gov/pubmed/18492274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-8-8
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