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Degradation of Functional Triose Phosphate Isomerase Protein Underlies sugarkill Pathology

Triose phosphate isomerase (TPI) deficiency glycolytic enzymopathy is a progressive neurodegenerative condition that remains poorly understood. The disease is caused exclusively by specific missense mutations affecting the TPI protein and clinically features hemolytic anemia, adult-onset neurologica...

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Detalhes bibliográficos
Main Authors: Seigle, Jacquelyn L., Celotto, Alicia M., Palladino, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429879/
https://ncbi.nlm.nih.gov/pubmed/18458110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.087551
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