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Schizosaccharomyces pombe Histone Acetyltransferase Mst1 (KAT5) Is an Essential Protein Required for Damage Response and Chromosome Segregation

Schizosaccharomyces pombe Mst1 is a member of the MYST family of histone acetyltransferases and is the likely ortholog of Saccharomyces cerevisiae Esa1 and human Tip60 (KAT5). We have isolated a temperature-sensitive allele of this essential gene. mst1 cells show a pleiotropic phenotype at the restr...

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Библиографические подробности
Главные авторы: Gómez, Eliana B., Nugent, Rebecca L., Laria, Sebastián, Forsburg, Susan L.
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429872/
https://ncbi.nlm.nih.gov/pubmed/18505873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.085779
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