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A comparative study of attenuated influenza viruses

Influenza A and influenza B viruses were adapted to growth at 25°C. When given to volunteer subjects, the viruses were attenuated but remained infective and antigenic. The minimum immunizing dose of an egg-adapted virus appeared to be 10(5.0) EID(50). Cloning by plaque selection at 25°C gave seed cu...

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Bibliografiske detaljer
Main Authors: Beare, A. S., Maassab, H. F., Tyrrell, D. A. J., Slepuškin, A. N., Hall, T. S.
Format: Artigo
Sprog:Inglês
Udgivet: 1971
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427844/
https://ncbi.nlm.nih.gov/pubmed/5316742
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