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Gonadotropin-regulated Testicular Helicase (DDX25), an Essential Regulator of Spermatogenesis, Prevents Testicular Germ Cell Apoptosis
Gonadotropin-regulated testicular helicase (GRTH)/DDX25 is an essential post-transcriptional regulator of spermatogenesis. In GRTH null mice severe apoptosis was observed in spermatocytes entering the metaphase of meiosis. Pro- and anti-apoptotic factors were found to be under GRTH regulation in com...
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Glavni autori: | , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Biochemistry and Molecular Biology
2008
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2427358/ https://ncbi.nlm.nih.gov/pubmed/18430733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708449200 |
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