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Gonadotropin-regulated Testicular Helicase (DDX25), an Essential Regulator of Spermatogenesis, Prevents Testicular Germ Cell Apoptosis

Gonadotropin-regulated testicular helicase (GRTH)/DDX25 is an essential post-transcriptional regulator of spermatogenesis. In GRTH null mice severe apoptosis was observed in spermatocytes entering the metaphase of meiosis. Pro- and anti-apoptotic factors were found to be under GRTH regulation in com...

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Autors principals: Gutti, Ravi K., Tsai-Morris, Chon-Hwa, Dufau, Maria L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427358/
https://ncbi.nlm.nih.gov/pubmed/18430733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708449200
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