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Mechanisms and Consequences of Small Supernumerary Marker Chromosomes: From Barbara McClintock to Modern Genetic-Counseling Issues

Supernumerary marker chromosomes (SMCs) are common, but their molecular content and mechanism of origin are often not precisely characterized. We analyzed all centromere regions to identify the junction between the unique chromosome arm and the pericentromeric repeats. A molecular-ruler clone panel...

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Bibliografiske detaljer
Main Authors: Baldwin, Erin L., May, Lorraine F., Justice, April N., Martin, Christa L., Ledbetter, David H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Human Genetics 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427313/
https://ncbi.nlm.nih.gov/pubmed/18252220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2007.10.013
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