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Splice Mutation in the Iron-Sulfur Cluster Scaffold Protein ISCU Causes Myopathy with Exercise Intolerance

A myopathy with severe exercise intolerance and myoglobinuria has been described in patients from northern Sweden, with associated deficiencies of succinate dehydrogenase and aconitase in skeletal muscle. We identified the gene for the iron-sulfur cluster scaffold protein ISCU as a candidate within...

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Autors principals: Mochel, Fanny, Knight, Melanie A., Tong, Wing-Hang, Hernandez, Dena, Ayyad, Karen, Taivassalo, Tanja, Andersen, Peter M., Singleton, Andrew, Rouault, Tracey A., Fischbeck, Kenneth H., Haller, Ronald G.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Human Genetics 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427212/
https://ncbi.nlm.nih.gov/pubmed/18304497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2007.12.012
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