3′ adenylation determines mRNA abundance and monitors completion of RNA editing in T. brucei mitochondria

Expression of the mitochondrial genome in protozoan parasite Trypanosoma brucei is controlled post-transcriptionally and requires extensive U-insertion/deletion mRNA editing. In mitochondrial extracts, 3′ adenylation reportedly influences degradation kinetics of synthetic edited and pre-edited mRNAs...

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Bibliographic Details
Main Authors: Etheridge, Ronald D, Aphasizheva, Inna, Gershon, Paul D, Aphasizhev, Ruslan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426725/
https://ncbi.nlm.nih.gov/pubmed/18464794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.87
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