Ryanodine Receptor Allosteric Coupling and the Dynamics of Calcium Sparks

Puffs and sparks are localized intracellular Ca(2+) elevations that arise from the cooperative activity of Ca(2+)-regulated inositol 1,4,5-trisphosphate receptors and ryanodine receptors clustered at Ca(2+) release sites on the surface of the endoplasmic reticulum or the sarcoplasmic reticulum. Whil...

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Bibliographic Details
Main Authors: Groff, Jeffrey R., Smith, Gregory D.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2008
Subjects:
Biophysical Theory and Modeling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426658/
https://ncbi.nlm.nih.gov/pubmed/18359795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.119982
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