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Structure and Dynamics of the Force-Generating Domain of Myosin Probed by Multifrequency Electron Paramagnetic Resonance

Spin-labeling and multifrequency EPR spectroscopy were used to probe the dynamic local structure of skeletal myosin in the region of force generation. Subfragment 1 (S1) of rabbit skeletal myosin was labeled with an iodoacetamide spin label at C707 (SH1). X- and W-band EPR spectra were recorded for...

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Main Authors: Nesmelov, Yuri E., Agafonov, Roman V., Burr, Adam R., Weber, Ralph T., Thomas, David D.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426653/
https://ncbi.nlm.nih.gov/pubmed/18339764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.124305
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