Identification of transcriptional regulatory cascades in retinoic acid-induced growth arrest of HepG2 cells

All-trans retinoic acid (ATRA) is a potent inducer of cell differentiation and growth arrest. Here, we investigated ATRA-induced regulatory cascades associated with growth arrest of the human hepatoma cell line HepG2. ATRA induced >2-fold changes in the expression of 402 genes including 55 linked...

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Main Authors: Nakanishi, Misato, Tomaru, Yasuhiro, Miura, Hisashi, Hayashizaki, Yoshihide, Suzuki, Masanori
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
Assuntos:
Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2425469/
https://ncbi.nlm.nih.gov/pubmed/18445634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn066
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