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Synthesis of the ABC Ring System of Azaspiracid. 2. A Systematic Study into the Effect of C(16) and C(17) Substitution on Bis-spirocyclization
A systematic study into the effect of C(16) and C(17) substitution on the stereochemical outcome of bis-spirocyclization to form the ABC ring system of azaspiracid is disclosed. Successful construction of the natural 10R,13R bis-spirocyclic stereochemistry has been accomplished on the C(16) benzylox...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2424254/ https://ncbi.nlm.nih.gov/pubmed/12074662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol026034o |
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