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Synthesis of the ABC Ring System of Azaspiracid. 2. A Systematic Study into the Effect of C(16) and C(17) Substitution on Bis-spirocyclization

A systematic study into the effect of C(16) and C(17) substitution on the stereochemical outcome of bis-spirocyclization to form the ABC ring system of azaspiracid is disclosed. Successful construction of the natural 10R,13R bis-spirocyclic stereochemistry has been accomplished on the C(16) benzylox...

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Hlavní autoři: Carter, Rich G., Graves, David E., Gronemeyer, Melissa A., Tschumper, Gregory S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424254/
https://ncbi.nlm.nih.gov/pubmed/12074662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol026034o
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