Silencing of Keratinocyte Growth Factor Receptor Restores 5-Fluorouracil and Tamoxifen Efficacy on Responsive Cancer Cells

BACKGROUND: Keratinocyte growth factor receptor (KGFR) is a splice variant of the FGFR2 gene expressed in epithelial cells. Activation of KGFR is a key factor in the regulation of physiological processes in epithelial cells such as proliferation, differentiation and wound healing. Alterations of KGF...

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Главные авторы: Rotolo, Sabrina, Ceccarelli, Simona, Romano, Ferdinando, Frati, Luigi, Marchese, Cinzia, Angeloni, Antonio
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2008
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424182/
https://ncbi.nlm.nih.gov/pubmed/18575591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002528
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