Microbial Translocation Is Associated with Increased Monocyte Activation and Dementia in AIDS Patients

Elevated plasma lipopolysaccharide (LPS), an indicator of microbial translocation from the gut, is a likely cause of systemic immune activation in chronic HIV infection. LPS induces monocyte activation and trafficking into brain, which are key mechanisms in the pathogenesis of HIV-associated dementi...

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Autores principales: Ancuta, Petronela, Kamat, Anupa, Kunstman, Kevin J., Kim, Eun-Young, Autissier, Patrick, Wurcel, Alysse, Zaman, Tauheed, Stone, David, Mefford, Megan, Morgello, Susan, Singer, Elyse J., Wolinsky, Steven M., Gabuzda, Dana
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424175/
https://ncbi.nlm.nih.gov/pubmed/18575590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002516
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