An essential role for SRC-activated STAT-3 in 14,15-EET–induced VEGF expression and angiogenesis

To understand the molecular mechanisms underlying 14,15-epoxyeicosatrienoic acid (14,15-EET)–induced angiogenesis, here we have studied the role of signal transducer and activator of transcription-3 (STAT-3). 14,15-EET stimulated the tyrosine phosphorylation of STAT-3 and its translocation from the...

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Detalhes bibliográficos
Main Authors: Cheranov, Sergey Y., Karpurapu, Manjula, Wang, Dong, Zhang, Baolin, Venema, Richard C., Rao, Gadiparthi N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424155/
https://ncbi.nlm.nih.gov/pubmed/18408167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-126680
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