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Recruitment of Tyrosine Phosphatase HCP (SHP-1) by the Killer Cell Inhibitory Receptor

Cytolysis of target cells by natural killer (NK) cells and by some cytotoxic T cells occurs unless prevented by inhibitory receptors that recognize MHC class I on target cells. Human NK cells express a p58 inhibitory receptor specific for HLA-C. We report association of the tyrosine phosphatase HCP...

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Autors principals: Burshtyn, Deborah N., Scharenberg, Andrew M., Wagtmann, Nicolai, Rajagopalan, Sumati, Berrada, Karim, Yi, Taolin, Kinet, Jean-Pierre, Long, Eric O.
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423819/
https://ncbi.nlm.nih.gov/pubmed/8574854
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