Modulation of Receptor Phosphorylation Contributes to Activation of Peroxisome Proliferator Activated Receptor α by Dehydroepiandrosterone and Other Peroxisome Proliferators

Dehydroepiandrosterone (DHEA), a C19 human adrenal steroid, activates peroxisome proliferator-activated receptor α (PPARα) in vivo but does not ligand-activate PPARα in transient transfection experiments. We demonstrate that DHEA regulates PPARα action by altering both the levels and phosphorylation...

Full description

Saved in:
Bibliographic Details
Main Authors: Tamasi, Viola, Miller, Kristy K. Michael, Ripp, Sharon L., Vila, Ermin, Geoghagen, Thomas E., Prough, Russell A.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423814/
https://ncbi.nlm.nih.gov/pubmed/18079279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.036780
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items