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Defects in ex vivo and in vivo growth and sensitivity to osmotic stress of group A Streptococcus caused by interruption of response regulator gene vicR

The regulator VicR of the two-component regulatory system VicRK is essential in several Gram-positive bacteria. However, we were able to generate an unconditional insertional mutant of group A Streptococcus vicR. This mutant grew well in rich media but not in non-immune human blood and serum, had at...

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Detalhes bibliográficos
Main Authors: Liu, Mengyao, Hanks, Tracey S., Zhang, Jinlian, McClure, Michael J., Siemsen, Daniel W., Elser, Julie L., Quinn, Mark T., Lei, Benfang
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423276/
https://ncbi.nlm.nih.gov/pubmed/16549661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.28706-0
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