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Solution Structure of a Hydrocarbon Stapled Peptide Inhibitor in Complex with Monomeric C-terminal Domain of HIV-1 Capsid

The human immunodeficiency virus type 1 (HIV-1) capsid protein plays a critical role in virus core particle assembly and is an important target for novel therapeutic strategies. In a previous study, we characterized the binding affinity of a hydrocarbon stapled helical peptide, NYAD-1, for the capsi...

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Detalhes bibliográficos
Main Authors: Bhattacharya, Shibani, Zhang, Hongtao, Debnath, Asim K., Cowburn, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423268/
https://ncbi.nlm.nih.gov/pubmed/18417468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800048200
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