The Apolipoprotein E-mimetic Peptide COG112 Inhibits the Inflammatory Response to Citrobacter rodentium in Colonic Epithelial Cells by Preventing NF-κB Activation

Inflammatory bowel disease arises from the interplay between luminal bacteria and the colonic mucosa. Targeted inhibition of pro-inflammatory pathways without global immunosuppression is highly desirable. Apolipoprotein (apo) E has immunomodulatory effects and synthetically derived apoE-mimetic pept...

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Détails bibliographiques
Auteurs principaux: Singh, Kshipra, Chaturvedi, Rupesh, Asim, Mohammad, Barry, Daniel P., Lewis, Nuruddeen D., Vitek, Michael P., Wilson, Keith T.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423260/
https://ncbi.nlm.nih.gov/pubmed/18417477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710530200
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