Mixed-effects Poisson regression analysis of adverse event reports: The relationship between antidepressants and suicide

A new statistical methodology is developed for the analysis of spontaneous adverse event (AE) reports from post-marketing drug surveillance data. The method involves both empirical Bayes (EB) and fully Bayes estimation of rate multipliers for each drug within a class of drugs, for a particular AE, b...

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Detalhes bibliográficos
Main Authors: Gibbons, Robert D., Segawa, Eisuke, Karabatsos, George, Amatya, Anup K., Bhaumik, Dulal K., Brown, C. Hendricks, Kapur, Kush, Marcus, Sue M., Hur, Kwan, Mann, J. John
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423233/
https://ncbi.nlm.nih.gov/pubmed/18404622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.3241
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