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A Method to Detect DNA Methyltransferase I Gene Transcription In Vitro in Aging Systems

Epigenetic alterations of DNA play key roles in determining gene structure and expression. Methylation of the 5-position of cytosine is thought to be the most common modification of the genome in mammals. Studies have generally shown that hypermethylation in gene regulatory regions is associated wit...

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Detalhes bibliográficos
Main Authors: Berletch, Joel B., Andrews, Lucy G., Tollefsbol, Trygve O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423211/
https://ncbi.nlm.nih.gov/pubmed/17634574
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