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A Method to Detect DNA Methyltransferase I Gene Transcription In Vitro in Aging Systems

Epigenetic alterations of DNA play key roles in determining gene structure and expression. Methylation of the 5-position of cytosine is thought to be the most common modification of the genome in mammals. Studies have generally shown that hypermethylation in gene regulatory regions is associated wit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Berletch, Joel B., Andrews, Lucy G., Tollefsbol, Trygve O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423211/
https://ncbi.nlm.nih.gov/pubmed/17634574
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