Predicting prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen

BACKGROUND: Estrogen receptor positive (ER+) breast cancers (BC) are heterogeneous with regard to their clinical behavior and response to therapies. The ER is currently the best predictor of response to the anti-estrogen agent tamoxifen, yet up to 30–40% of ER+BC will relapse despite tamoxifen treat...

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Main Authors: Loi, Sherene, Haibe-Kains, Benjamin, Desmedt, Christine, Wirapati, Pratyaksha, Lallemand, Françoise, Tutt, Andrew M, Gillet, Cheryl, Ellis, Paul, Ryder, Kenneth, Reid, James F, Daidone, Maria G, Pierotti, Marco A, Berns, Els MJJ, Jansen, Maurice PHM, Foekens, John A, Delorenzi, Mauro, Bontempi, Gianluca, Piccart, Martine J, Sotiriou, Christos
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423197/
https://ncbi.nlm.nih.gov/pubmed/18498629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-239
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