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Histone Deacetylase 5 Acquires Calcium/Calmodulin-Dependent Kinase II Responsiveness by Oligomerization with Histone Deacetylase 4

Calcium/calmodulin-dependent protein kinase II (CaMKII) phosphorylates histone deacetylase 4 (HDAC4), a class IIa HDAC, resulting in the cytosolic accumulation of HDAC4 and the derepression of the transcription factor myocyte enhancer factor 2. Phosphorylation by CaMKII requires docking of the kinas...

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Bibliographische Detailangaben
Hauptverfasser: Backs, Johannes, Backs, Thea, Bezprozvannaya, Svetlana, McKinsey, Timothy A., Olson, Eric N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423150/
https://ncbi.nlm.nih.gov/pubmed/18332106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01611-07
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