The Chlamydia trachomatis Plasmid Is a Transcriptional Regulator of Chromosomal Genes and a Virulence Factor

Chlamydia trachomatis possesses a cryptic 7.5-kb plasmid of unknown function. Here, we describe a comprehensive molecular and biological characterization of the naturally occurring plasmidless human C. trachomatis strain L2(25667R). We found that despite minimal chromosomal polymorphisms, the LGV st...

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Detalhes bibliográficos
Main Authors: Carlson, John H., Whitmire, William M., Crane, Deborah D., Wicke, Luke, Virtaneva, Kimmo, Sturdevant, Daniel E., Kupko, John J., Porcella, Stephen F., Martinez-Orengo, Neysha, Heinzen, Robert A., Kari, Laszlo, Caldwell, Harlan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423098/
https://ncbi.nlm.nih.gov/pubmed/18347045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00102-08
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