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RAD59 is Required for Efficient Repair of Simultaneous Double-Strand Breaks Resulting in Translocations in Saccharomyces cerevisiae

Exposure to ionizing radiation results in a variety of genome rearrangements that have been linked to tumor formation. Many of these rearrangements are thought to arise from the repair of double-strand breaks (DSBs) by several mechanisms, including homologous recombination (HR) between repetitive se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pannunzio, Nicholas R., Manthey, Glenn M., Bailis, Adam M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2422859/
https://ncbi.nlm.nih.gov/pubmed/18373960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.02.003
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