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Mitochondrial Uncoupling Protein-2 Mediates Steatotic Liver Injury following Ischemia/Reperfusion

Steatotic livers are not used for transplantation because they have a reduced tolerance for ischemic events with reduced ATP levels and greater levels of cellular necrosis, which ultimately result in total organ failure. Mitochondrial uncoupling protein-2 (UCP2) is highly expressed in steatotic live...

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Bibliographic Details
Main Authors: Evans, Zachary P., Ellett, Justin D., Schmidt, Michael G., Schnellmann, Rick G., Chavin, Kenneth D.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2417178/
https://ncbi.nlm.nih.gov/pubmed/18086675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706784200
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