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Acute toxicity of aminoglycoside antibiotics as an aid in detecting botulism.

Gentamicin sulfate or neomycin sulfate injected intraperitoneally into 24- to 27-g mice at a dose of 6.2 mg per mouse elicited botulism-like responses in less than 30 min, but a dose of 3.1 mg per mouse had no observable effect. The normally nontoxic 3.1-mg aminoglycoside dose aggravated the illness...

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Détails bibliographiques
Publié dans:Appl Environ Microbiol
Auteurs principaux: Wang, Y C, Burr, D H, Korthals, G J, Sugiyama, H
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6508309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.48.5.951-955.1984
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