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In Vivo Efficacy of β-Cyclodextrin Derivatives against Anthrax Lethal Toxin
We evaluated the in vivo efficacy of three β-cyclodextrin derivatives that block the anthrax protective antigen pore. These compounds were at least 15-fold more potent than previously described β-cyclodextrins in protecting against anthrax lethal toxin in a rat model. One of the drugs was shown to p...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2415786/ https://ncbi.nlm.nih.gov/pubmed/18378717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00009-08 |
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