Microbial models of mammalian metabolism: microbial reduction and oxidation of pentoxifylline.

Fourteen microorganisms, including fungi, yeasts, and bacteria, were screened for their ability to metabolize the xanthine drug pentoxifylline. Thirteen cultures either reduced the drug to the alcohol metabolite or oxidatively cleaved the ketonic side chain to homologous carboxylic acid metabolites....

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Davis, P J, Yang, S K, Smith, R V
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241512/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6486781/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.48.2.327-331.1984
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