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Correlation between NK function and response to trastuzumab in metastatic breast cancer patients
BACKGROUND: Trastuzumab is a monoclonal antibody selectively directed against Her2 and approved for the treatment of Her2 overexpressing breast cancer patients. Its proposed mechanisms of action include mediation of antibody-dependent cellular cytotoxicity (ADCC) by triggering FcγRIII on natural kil...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2415031/ https://ncbi.nlm.nih.gov/pubmed/18485193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-6-25 |
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