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c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation

c-Abl is a ubiquitously expressed protein tyrosine kinase activated by DNA damage and implicated in two responses: cell cycle arrest and apoptosis. The downstream pathways by which c-Abl induces these responses remain unclear. We examined the effect of overexpression of c-Abl on the activation of mi...

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Bibliografiska uppgifter
Huvudupphovsmän: Cong, Feng, Goff, Stephen P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC24148/
https://ncbi.nlm.nih.gov/pubmed/10570156
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