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Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation.

The 243R E1A protein can act in synergy with cyclic AMP to induce AP-1 DNA-binding activity and c-fos mRNA in mouse S49 cells. A series of deletion mutants was used to identify two domains of the 243R protein that were required for these effects. Interestingly, these domains correlated precisely wit...

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Udgivet i:J Virol
Principais autores: Gedrich, R W, Bayley, S T, Engel, D A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1326646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.10.5849-5859.1992
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