The prototypical Epstein-Barr virus-transformed lymphoblastoid cell line IB4 is an unusual variant containing integrated but no episomal viral DNA.

IB4 is a prototype, latently Epstein-Barr virus (EBV)-infected, lymphoblastoid cell line. We show here that IB4 contains only integrated EBV genomes. Episomal EBV DNA is not detected by Gardella gel analysis or in situ hybridization. Restriction enzyme mapping indicates that the EBV genomes first ci...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Hurley, E A, Klaman, L D, Agger, S, Lawrence, J B, Thorley-Lawson, D A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241437/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.7.3958-3963.1991
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