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Protein Phosphatase 2A Is Targeted to Cell Division Control Protein 6 by a Calcium-binding Regulatory Subunit

The cell division control protein 6 (Cdc6) is essential for formation of pre-replication complexes at origins of DNA replication. Phosphorylation of Cdc6 by cyclin-dependent kinases inhibits ubiquitination of Cdc6 by APC/C(cdh1) and degradation by the proteasome. Experiments described here show that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Davis, Anthony J., Yan, Zhen, Martinez, Bobbie, Mumby, Marc C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2414307/
https://ncbi.nlm.nih.gov/pubmed/18397887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710313200
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