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ICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated.

Infected cell protein 4 (ICP4), the product of the alpha 4 gene, regulates herpes simplex virus 1 and herpes simplex virus 2 gene expression at the transcriptional level both positively and negatively. Previous studies have shown that ICP4 is extensively modified posttranslationally. We report that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Blaho, J A, Roizman, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241406/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645791/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.7.3759-3769.1991
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