Functional tolerance of the human immunodeficiency virus type 1 envelope signal peptide to mutations in the amino-terminal and hydrophobic regions.

We demonstrated that the leader sequence of the human immunodeficiency virus type 1 envelope functions as signal peptide (SP) despite low scoring in a prediction program. As expected for SP, the hydrophobic core (HC) is essential, and no other sequence could compensate for HC deletion. Contrary to o...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ellerbrok, H, D'Auriol, L, Vaquero, C, Sitbon, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241382/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1629966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.8.5114-5118.1992
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