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Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins.

The E6 oncoproteins encoded by the cancer-associated human papillomaviruses (HPVs) can associate with and promote the degradation of wild-type p53 in vitro. To gain further insight into this process, the ability of HPV-16 E6 to complex with and promote the degradation of mutant forms of p53 was stud...

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Bibliographic Details
Published in:J Virol
Main Authors: Scheffner, M, Takahashi, T, Huibregtse, J M, Minna, J D, Howley, P M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.8.5100-5105.1992
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