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Human influenza virus hemagglutinin with high sensitivity to proteolytic activation.

To examine the prerequisites for cleavage activation of the hemagglutinin of human influenza viruses, a cDNA clone obtained from strain A/Port Chalmers/1/73 (serotype H3) was subjected to site-directed mutagenesis and expressed in CV-1 cells by using a simian virus 40 vector. The number of basic res...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Ohuchi, R, Ohuchi, M, Garten, W, Klenk, H D
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2041080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.7.3530-3537.1991
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