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Analysis of large deletions in BRCA1, BRCA2 and PALB2 genes in Finnish breast and ovarian cancer families

BACKGROUND: BRCA1 and BRCA2 are the two most important genes associated with familial breast and ovarian cancer susceptibility. In addition, PALB2 has recently been identified as a breast cancer susceptibility gene in several populations. Here we have evaluated whether large genomic rearrangement in...

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Detalhes bibliográficos
Main Authors: Pylkäs, Katri, Erkko, Hannele, Nikkilä, Jenni, Sólyom, Szilvia, Winqvist, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413256/
https://ncbi.nlm.nih.gov/pubmed/18501021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-146
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