Spectrum and characterisation of BRCA1 and BRCA2 deleterious mutations in high-risk Czech patients with breast and/or ovarian cancer

BACKGROUND: The incidence of breast cancer has doubled over the past 20 years in the Czech Republic. Hereditary factors may be a cause of young onset, bilateral breast or ovarian cancer, and familial accumulation of the disease. BRCA1 and BRCA2 mutations account for an important fraction of heredita...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Machackova, Eva, Foretova, Lenka, Lukesova, Mirka, Vasickova, Petra, Navratilova, Marie, Coene, Ilse, Pavlu, Hana, Kosinova, Veronika, Kuklova, Jitka, Claes, Kathleen
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413254/
https://ncbi.nlm.nih.gov/pubmed/18489799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-140
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы