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Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

Expression of the epidermal growth factor receptor (EGFR), a receptor tyrosine kinase associated with cell proliferation and survival, is overactive in many tumors of epithelial origin. Blockade of the kinase activity of EGFR has been used for cancer therapy; however, by itself, it does not seem to...

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Sonraí Bibleagrafaíochta
Main Authors: Weihua, Zhang, Tsan, Rachel, Huang, Wei-Chien, Wu, Qiuyu, Chiu, Chao-Hua, Fidler, Isaiah J., Hung, Mien-Chie
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413063/
https://ncbi.nlm.nih.gov/pubmed/18455122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.03.015
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