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Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling
The mitogen-activated protein kinase (MAPK) pathway plays a critical role in Toll-like receptor (TLR) signaling. MAPK phosphatase-1 (MKP-1) inhibits the MAPK pathway and decreases TLR signaling, but the regulation of MKP-1 is not completely understood. We now show that MKP-1 is acetylated, and that...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413043/ https://ncbi.nlm.nih.gov/pubmed/18504304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071728 |
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