“Re-educating” tumor-associated macrophages by targeting NF-κB

The nuclear factor κB (NF-κB) signaling pathway is important in cancer-related inflammation and malignant progression. Here, we describe a new role for NF-κB in cancer in maintaining the immunosuppressive phenotype of tumor-associated macrophages (TAMs). We show that macrophages are polarized via in...

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Detalhes bibliográficos
Main Authors: Hagemann, Thorsten, Lawrence, Toby, McNeish, Iain, Charles, Kellie A., Kulbe, Hagen, Thompson, Richard G., Robinson, Stephen C., Balkwill, Frances R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413024/
https://ncbi.nlm.nih.gov/pubmed/18490490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080108
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