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Pioglitazone Enhances Mitochondrial Biogenesis and Ribosomal Protein Biosynthesis in Skeletal Muscle in Polycystic Ovary Syndrome

Insulin resistance is a common metabolic abnormality in women with PCOS and leads to an elevated risk of type 2 diabetes. Studies have shown that thiazolidinediones (TZDs) improve metabolic disturbances in PCOS patients. We hypothesized that the effect of TZDs in PCOS is, in part, mediated by change...

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Detalhes bibliográficos
Main Authors: Skov, Vibe, Glintborg, Dorte, Knudsen, Steen, Tan, Qihua, Jensen, Thomas, Kruse, Torben A., Beck-Nielsen, Henning, Højlund, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413008/
https://ncbi.nlm.nih.gov/pubmed/18560589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002466
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