Activation of simian virus 40 transcription in vitro by T antigen.

Simian virus 40 is repressed when the viral early gene product large tumor antigen (TAg) binds to specific sites within the viral origin and DNA replication ensues. Late transcription is activated by TAg, even in the absence of viral DNA replication. We show here that TAg produced in human 293 cells...

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Bibliographic Details
Main Authors: Coulombe, J, Berger, L, Smith, D B, Hehl, R K, Wildeman, A G
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC241274/
https://ncbi.nlm.nih.gov/pubmed/1318422
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