Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance.

The 27-kDa Rex trans-acting protein appears to be essential for replication of human T-cell leukemia virus type I. Mutations introduced outside of the Rex RNA-binding domain-nucleolar localization signal display either wild-type activity or, conversely, yield dominant-negative proteins. We generated...

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Pubblicato in:	J Virol
Autori principali:	Weichselbraun, I, Berger, J, Dobrovnik, M, Bogerd, H, Grassmann, R, Greene, W C, Hauber, J, Böhnlein, E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1602559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.7.4540-4545.1992
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